![2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole structure](/static/products/1486/148692-48-2.webp)
2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole
TL;DR: 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole (CAS 148692-48-2) is a chemical compound with molecular formula C18H18N4O and molecular weight 306.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1H-indol-2-yl-(4-pyridin-2-ylpiperazin-1-yl)methanone
Also Known As: 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole, 1H-indol-2-yl-(4-pyridin-2-ylpiperazin-1-yl)methanone, INDOL-2-YL 4-(2-PYRIDYL)PIPERAZINYL KETONE, (1H-indol-2-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone, 1H-indol-2-yl-[4-(2-pyridyl)piperazin-1-yl]methanone
| Molecular Formula | C18H18N4O |
|---|---|
| Molecular Weight | 306.15 g/mol |
| LogP | 2.5253 |
| Topological Polar Surface Area | 52.23 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 306.14807 |
| Heavy Atoms | 23 |
| Complexity | 786.1686 |
Chemical Identifiers
| CAS Number | 148692-48-2 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=N2)C(=O)C3=CC4=CC=CC=C4N3 |
Product Overview
2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole (CAS 148692-48-2), with molecular formula C18H18N4O and molecular weight 306.15 g/mol. IUPAC: 1H-indol-2-yl-(4-pyridin-2-ylpiperazin-1-yl)methanone.
Chemical Property Profile of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole
Property Insights of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole
The XLogP value of 2.5253 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole. With a topological polar surface area (TPSA) of 52.23 Ų, 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole?
The CAS number of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole is 148692-48-2.
What is the molecular formula of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole?
The molecular formula of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole is C18H18N4O.
What is the molecular weight of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole?
The molecular weight of 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole is 306.15 g/mol.
Where can I buy 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole?
You can request a quote for 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-(pyridin-2-yl)piperazine-1-carbonyl]-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.