GR 127935
TL;DR: GR 127935 (CAS 148672-13-3) is a chemical compound with molecular formula C29H31N5O3 and molecular weight 497.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
Also Known As: GR 127935, GR 127935 hydrochloride, Lopac-G-5793, GTPL14, N-(4-Methoxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide
| Molecular Formula | C29H31N5O3 |
|---|---|
| Molecular Weight | 497.24 g/mol |
| LogP | 4.9 |
| Topological Polar Surface Area | 83.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 497.24268 |
| Heavy Atoms | 37 |
| Complexity | 739.0 |
Chemical Identifiers
| CAS Number | 148672-13-3 |
|---|---|
| SMILES | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C |
| InChIKey | YDBCEBYHYKAFRX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
GR 127935 (CAS 148672-13-3), with molecular formula C29H31N5O3 and molecular weight 497.24 g/mol. IUPAC: N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide.
Chemical Property Profile of GR 127935
Property Insights of GR 127935
The XLogP value of 4.9 indicates that GR 127935 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.7 Ų falls within the moderate polarity range, balancing permeability and solubility for GR 127935. Following Lipinski's Rule of Five, GR 127935 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GR 127935?
The CAS number of GR 127935 is 148672-13-3.
What is the molecular formula of GR 127935?
The molecular formula of GR 127935 is C29H31N5O3.
What is the molecular weight of GR 127935?
The molecular weight of GR 127935 is 497.24 g/mol.
Where can I buy GR 127935?
You can request a quote for GR 127935 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GR 127935?
Yes, KEHONG BIO provides custom synthesis services for GR 127935 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.