Zidovudine impurity G
TL;DR: Zidovudine impurity G (CAS 148665-49-0) is a chemical compound with molecular formula C20H25N7O8 and molecular weight 491.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-3-[(2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Zidovudine impurity G, Zidovudine EP Impurity G, 3-(Thymidinyl)AZT, Zidovudine Impurity 14, Zidovudine USP Impurity G
| Molecular Formula | C20H25N7O8 |
|---|---|
| Molecular Weight | 491.18 g/mol |
| LogP | -0.8 |
| Topological Polar Surface Area | 163.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 6 |
| Exact Mass | 491.17645 |
| Heavy Atoms | 35 |
| Complexity | 1050.0 |
Chemical Identifiers
| CAS Number | 148665-49-0 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N3C(=O)C(=CN(C3=O)[C@H]4C[C@@H]([C@H](O4)CO)N=[N+]=[N-])C |
| InChIKey | FOSHPJRCRHGLRP-KPRKPIBOSA-N |
Product Overview
Zidovudine impurity G (CAS 148665-49-0), with molecular formula C20H25N7O8 and molecular weight 491.18 g/mol. IUPAC: 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-3-[(2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of Zidovudine impurity G
Property Insights of Zidovudine impurity G
The XLogP value of -0.8 indicates that Zidovudine impurity G is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 163.0 Ų indicates high polarity, suggesting Zidovudine impurity G may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Zidovudine impurity G has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Zidovudine impurity G?
The CAS number of Zidovudine impurity G is 148665-49-0.
What is the molecular formula of Zidovudine impurity G?
The molecular formula of Zidovudine impurity G is C20H25N7O8.
What is the molecular weight of Zidovudine impurity G?
The molecular weight of Zidovudine impurity G is 491.18 g/mol.
Where can I buy Zidovudine impurity G?
You can request a quote for Zidovudine impurity G directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Zidovudine impurity G?
Yes, KEHONG BIO provides custom synthesis services for Zidovudine impurity G and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.