L-732,138
TL;DR: L-732,138 (CAS 148451-96-1) is a chemical compound with molecular formula C22H18F6N2O3 and molecular weight 472.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate
Also Known As: 3,5-Bis(tfm)Bz nactrp, L-732,138, L-732138, N-Acetyl-L-tryptophan, Lopac-A-5330
| Molecular Formula | C22H18F6N2O3 |
|---|---|
| Molecular Weight | 472.12 g/mol |
| LogP | 4.7 |
| Topological Polar Surface Area | 71.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 7 |
| Exact Mass | 472.12216 |
| Heavy Atoms | 33 |
| Complexity | 677.0 |
| Solubility | 3.4 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 148451-96-1 |
|---|---|
| SMILES | CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F |
| InChIKey | BYYQYXVAWXAYQC-IBGZPJMESA-N |
Product Overview
L-732,138 (CAS 148451-96-1), with molecular formula C22H18F6N2O3 and molecular weight 472.12 g/mol. IUPAC: [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate.
Chemical Property Profile of L-732,138
Property Insights of L-732,138
The XLogP value of 4.7 indicates that L-732,138 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.2 Ų falls within the moderate polarity range, balancing permeability and solubility for L-732,138. Following Lipinski's Rule of Five, L-732,138 has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-732,138?
The CAS number of L-732,138 is 148451-96-1.
What is the molecular formula of L-732,138?
The molecular formula of L-732,138 is C22H18F6N2O3.
What is the molecular weight of L-732,138?
The molecular weight of L-732,138 is 472.12 g/mol.
Where can I buy L-732,138?
You can request a quote for L-732,138 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-732,138?
Yes, KEHONG BIO provides custom synthesis services for L-732,138 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.