NK 250 structure

NK 250

TL;DR: NK 250 (CAS 148416-85-7) is a chemical compound with molecular formula C26H27N3O4S2 and molecular weight 509.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

NK 250

bis(pyridin-4-ylmethyl) 2,6-dimethyl-4-(6-methyl-2,3-dihydro-1,4-dithiin-5-yl)-1,4-dihydropyridine-3,5-dicarboxylate

Also Known As: NK 250, NIK250, NCI60_020780, bis(pyridin-4-ylmethyl) 2,6-dimethyl-4-(6-methyl-2,3-dihydro-1,4-dithiin-5-yl)-1,4-dihydropyridine-3,5-dicarboxylate, 2,6-Dimethyl-1,4-dihydro-4-[(5,6-dihydro-3-methyl-1,4-dithiin)-2-yl]-3,5-pyridinedicarboxylic acid bis[(pyridin-4-yl)methyl] ester

CAS: 148416-85-7
Molecular Formula C26H27N3O4S2
Molecular Weight 509.14 g/mol
LogP 3.2
Topological Polar Surface Area 141.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 9
Rotatable Bonds 9
Exact Mass 509.1443
Heavy Atoms 35
Complexity 846.0

Chemical Identifiers

CAS Number 148416-85-7
SMILES CC1=C(C(C(=C(N1)C)C(=O)OCC2=CC=NC=C2)C3=C(SCCS3)C)C(=O)OCC4=CC=NC=C4
InChIKey WKCXIRURXIDOND-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (3 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

NK 250 (CAS 148416-85-7), with molecular formula C26H27N3O4S2 and molecular weight 509.14 g/mol. IUPAC: bis(pyridin-4-ylmethyl) 2,6-dimethyl-4-(6-methyl-2,3-dihydro-1,4-dithiin-5-yl)-1,4-dihydropyridine-3,5-dicarboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NK 250

XLogP
3.2
TPSA (Topological Polar Surface Area)
141.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
9
Rotatable Bonds
9
Heavy Atoms
35
Complexity
846.0
Exact Mass
509.1443
Monoisotopic Mass
509.1443
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NK 250

The XLogP value of 3.2 indicates that NK 250 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 141.0 Ų indicates high polarity, suggesting NK 250 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, NK 250 has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NK 250?

The CAS number of NK 250 is 148416-85-7.

What is the molecular formula of NK 250?

The molecular formula of NK 250 is C26H27N3O4S2.

What is the molecular weight of NK 250?

The molecular weight of NK 250 is 509.14 g/mol.

Where can I buy NK 250?

You can request a quote for NK 250 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NK 250?

Yes, KEHONG BIO provides custom synthesis services for NK 250 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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