Doripenem
TL;DR: Doripenem (CAS 148016-81-3) is a chemical compound with molecular formula C15H24N4O6S2 and molecular weight 420.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Also Known As: Doripenem, Doribax, Finibax, Doripenem hydrate, doripenemum
| Molecular Formula | C15H24N4O6S2 |
|---|---|
| Molecular Weight | 420.11 g/mol |
| LogP | -3.4 |
| Topological Polar Surface Area | 196.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 7 |
| Exact Mass | 420.11374 |
| Heavy Atoms | 27 |
| Complexity | 780.0 |
Chemical Identifiers
| CAS Number | 148016-81-3 |
|---|---|
| SMILES | C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)CNS(=O)(=O)N)C(=O)O)[C@@H](C)O |
| InChIKey | AVAACINZEOAHHE-VFZPANTDSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Doripenem (CAS 148016-81-3), with molecular formula C15H24N4O6S2 and molecular weight 420.11 g/mol. IUPAC: (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid.
Chemical Property Profile of Doripenem
Property Insights of Doripenem
The XLogP value of -3.4 indicates that Doripenem is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 196.0 Ų indicates high polarity, suggesting Doripenem may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Doripenem has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Doripenem?
The CAS number of Doripenem is 148016-81-3.
What is the molecular formula of Doripenem?
The molecular formula of Doripenem is C15H24N4O6S2.
What is the molecular weight of Doripenem?
The molecular weight of Doripenem is 420.11 g/mol.
Where can I buy Doripenem?
You can request a quote for Doripenem directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Doripenem?
Yes, KEHONG BIO provides custom synthesis services for Doripenem and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.