Methyl Glycyrrhetinate structure

Methyl Glycyrrhetinate

TL;DR: Methyl Glycyrrhetinate (CAS 1477-44-7) is a chemical compound with molecular formula C31H48O4 and molecular weight 484.36 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate

Also Known As: Methyl glycyrrhetinate, Methyl glycyrrhetate, Methyl 18-beta-glycyrrhetate, 18ss-GLA methyl ester, Methyl 18-beta-glycyrrhetinate

CAS: 1477-44-7
Molecular Formula C31H48O4
Molecular Weight 484.36 g/mol
LogP 6.7
Topological Polar Surface Area 63.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 484.35526
Heavy Atoms 35
Complexity 980.0

Chemical Identifiers

CAS Number 1477-44-7
SMILES C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)OC
InChIKey RMIVRCBSQPCSCQ-BDANYOJNSA-N

Product Overview

Methyl Glycyrrhetinate (CAS 1477-44-7), with molecular formula C31H48O4 and molecular weight 484.36 g/mol. IUPAC: methyl (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Methyl Glycyrrhetinate

XLogP
6.7
TPSA (Topological Polar Surface Area)
63.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
35
Complexity
980.0
Exact Mass
484.35526
Monoisotopic Mass
484.35526
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Methyl Glycyrrhetinate

The XLogP value of 6.7 indicates that Methyl Glycyrrhetinate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Methyl Glycyrrhetinate. Following Lipinski's Rule of Five, Methyl Glycyrrhetinate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Methyl Glycyrrhetinate?

The CAS number of Methyl Glycyrrhetinate is 1477-44-7.

What is the molecular formula of Methyl Glycyrrhetinate?

The molecular formula of Methyl Glycyrrhetinate is C31H48O4.

What is the molecular weight of Methyl Glycyrrhetinate?

The molecular weight of Methyl Glycyrrhetinate is 484.36 g/mol.

Where can I buy Methyl Glycyrrhetinate?

You can request a quote for Methyl Glycyrrhetinate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Methyl Glycyrrhetinate?

Yes, KEHONG BIO provides custom synthesis services for Methyl Glycyrrhetinate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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