Indosol
TL;DR: Indosol (CAS 147236-05-3) is a chemical compound with molecular formula C23H27ClN2O7 and molecular weight 478.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
Also Known As: Indosol, Indosol eye drop, Indomethacin tromethamine, 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate (salt), 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
| Molecular Formula | C23H27ClN2O7 |
|---|---|
| Molecular Weight | 478.15 g/mol |
| LogP | 1.58812 |
| Topological Polar Surface Area | 155.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 478.15067 |
| Heavy Atoms | 33 |
| Complexity | 560.0 |
Chemical Identifiers
| CAS Number | 147236-05-3 |
|---|---|
| SMILES | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O.C(C(CO)(CO)N)O |
| InChIKey | VHDFCBMXCOUFOE-UHFFFAOYSA-N |
Product Overview
Indosol (CAS 147236-05-3), with molecular formula C23H27ClN2O7 and molecular weight 478.15 g/mol. IUPAC: 2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid.
Chemical Property Profile of Indosol
Property Insights of Indosol
The XLogP value of 1.58812 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Indosol. The TPSA of 155.0 Ų indicates high polarity, suggesting Indosol may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Indosol has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Indosol?
The CAS number of Indosol is 147236-05-3.
What is the molecular formula of Indosol?
The molecular formula of Indosol is C23H27ClN2O7.
What is the molecular weight of Indosol?
The molecular weight of Indosol is 478.15 g/mol.
Where can I buy Indosol?
You can request a quote for Indosol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Indosol?
Yes, KEHONG BIO provides custom synthesis services for Indosol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.