2'-F-dU Phosphoramidite
TL;DR: 2'-F-dU Phosphoramidite (CAS 146954-75-8) is a chemical compound with molecular formula C39H46FN4O8P and molecular weight 748.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Also Known As: 2'-F-dU Phosphoramidite, DMT-2'Fluoro-dU Phosphoramidite, 2'-F-dUPhosphoramidite, 2'-F-U Phosphoramidite, 2/'-F-Du Phosphoramidite
| Molecular Formula | C39H46FN4O8P |
|---|---|
| Molecular Weight | 748.30 g/mol |
| LogP | 6.45918 |
| Topological Polar Surface Area | 137.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 17 |
| Exact Mass | 748.3037 |
| Heavy Atoms | 53 |
| Complexity | 1861.899 |
Chemical Identifiers
| CAS Number | 146954-75-8 |
|---|---|
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Product Overview
2'-F-dU Phosphoramidite (CAS 146954-75-8), with molecular formula C39H46FN4O8P and molecular weight 748.30 g/mol. IUPAC: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile.
Chemical Property Profile of 2'-F-dU Phosphoramidite
Property Insights of 2'-F-dU Phosphoramidite
The XLogP value of 6.45918 indicates that 2'-F-dU Phosphoramidite is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 137.27 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-F-dU Phosphoramidite. Following Lipinski's Rule of Five, 2'-F-dU Phosphoramidite has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-F-dU Phosphoramidite?
The CAS number of 2'-F-dU Phosphoramidite is 146954-75-8.
What is the molecular formula of 2'-F-dU Phosphoramidite?
The molecular formula of 2'-F-dU Phosphoramidite is C39H46FN4O8P.
What is the molecular weight of 2'-F-dU Phosphoramidite?
The molecular weight of 2'-F-dU Phosphoramidite is 748.30 g/mol.
Where can I buy 2'-F-dU Phosphoramidite?
You can request a quote for 2'-F-dU Phosphoramidite directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-F-dU Phosphoramidite?
Yes, KEHONG BIO provides custom synthesis services for 2'-F-dU Phosphoramidite and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.