10-Ethylaminopterin
TL;DR: 10-Ethylaminopterin (CAS 14683-83-1) is a chemical compound with molecular formula C21H24N8O5 and molecular weight 468.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-ethylamino]benzoyl]amino]pentanedioic acid
Also Known As: Ethylaminopterin, 10-Ethylaminopterin, N10-Ethylaminopterin, L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)ethylamino)benzoyl)-, n-(4-{[(2,4-diaminopteridin-6-yl)methyl](ethyl)amino}benzoyl)-l-glutamic acid
| Molecular Formula | C21H24N8O5 |
|---|---|
| Molecular Weight | 468.19 g/mol |
| LogP | -1.5 |
| Topological Polar Surface Area | 211.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 10 |
| Exact Mass | 468.18695 |
| Heavy Atoms | 34 |
| Complexity | 719.0 |
Chemical Identifiers
| CAS Number | 14683-83-1 |
|---|---|
| SMILES | CCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
| InChIKey | POZRJDDKFDDOQR-AWEZNQCLSA-N |
Product Overview
10-Ethylaminopterin (CAS 14683-83-1), with molecular formula C21H24N8O5 and molecular weight 468.19 g/mol. IUPAC: (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-ethylamino]benzoyl]amino]pentanedioic acid.
Chemical Property Profile of 10-Ethylaminopterin
Property Insights of 10-Ethylaminopterin
The XLogP value of -1.5 indicates that 10-Ethylaminopterin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 211.0 Ų indicates high polarity, suggesting 10-Ethylaminopterin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 10-Ethylaminopterin has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Ethylaminopterin?
The CAS number of 10-Ethylaminopterin is 14683-83-1.
What is the molecular formula of 10-Ethylaminopterin?
The molecular formula of 10-Ethylaminopterin is C21H24N8O5.
What is the molecular weight of 10-Ethylaminopterin?
The molecular weight of 10-Ethylaminopterin is 468.19 g/mol.
Where can I buy 10-Ethylaminopterin?
You can request a quote for 10-Ethylaminopterin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Ethylaminopterin?
Yes, KEHONG BIO provides custom synthesis services for 10-Ethylaminopterin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.