Dutomycin structure

Dutomycin

TL;DR: Dutomycin (CAS 146663-67-4) is a chemical compound with molecular formula C44H54O17 and molecular weight 854.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] (Z,4R)-2,4-dimethylhept-2-enoate

Also Known As: Dutomycin, EX-A14851, HY-N14738, [(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] (Z,4R)-2,4-dimethylhept-2-enoate, 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-((5-((2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-alpha-L-xylo-hexopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, (2S-(2alpha(6aR*,10S*,10aS*),5beta(2Z,4S*),6alpha))-

CAS: 146663-67-4
Molecular Formula C44H54O17
Molecular Weight 854.34 g/mol
LogP 3.27032
Topological Polar Surface Area 258.95 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 17
Rotatable Bonds 11
Exact Mass 854.3361
Heavy Atoms 61
Complexity 2162.5918

Chemical Identifiers

CAS Number 146663-67-4
SMILES CCC[C@@H](C)/C=C(/C)\C(=O)O[C@@H]1[C@@H](O[C@H](C[C@@]1(C)O)O[C@H]2CC[C@@H](O[C@@H]2C)O[C@@H]3C(=O)C(=C([C@@]4([C@]3(CC5=C(C6=C(C(=O)C=C(C6=O)OC)C(=C5C4=O)O)C)O)O)O)C(=O)C)C

Product Overview

Dutomycin (CAS 146663-67-4), with molecular formula C44H54O17 and molecular weight 854.34 g/mol. IUPAC: [(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] (Z,4R)-2,4-dimethylhept-2-enoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dutomycin

XLogP
3.27032
TPSA (Topological Polar Surface Area)
258.95
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
17
Rotatable Bonds
11
Heavy Atoms
61
Complexity
2162.5918
Exact Mass
854.3361
Monoisotopic Mass
854.3361
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dutomycin

The XLogP value of 3.27032 indicates that Dutomycin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 258.95 Ų indicates high polarity, suggesting Dutomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Dutomycin has 5 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dutomycin?

The CAS number of Dutomycin is 146663-67-4.

What is the molecular formula of Dutomycin?

The molecular formula of Dutomycin is C44H54O17.

What is the molecular weight of Dutomycin?

The molecular weight of Dutomycin is 854.34 g/mol.

Where can I buy Dutomycin?

You can request a quote for Dutomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dutomycin?

Yes, KEHONG BIO provides custom synthesis services for Dutomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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