2'-Hydroxy-5'-(trifluoromethoxy)acetophenone
TL;DR: 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone (CAS 146575-64-6) is a chemical compound with molecular formula C9H7F3O3 and molecular weight 220.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-hydroxy-5-(trifluoromethoxy)phenyl]ethanone
Also Known As: 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone, 1-[2-hydroxy-5-(trifluoromethoxy)phenyl]ethanone, 1-(2-Hydroxy-5-(trifluoromethoxy)phenyl)ethanone, 2-Hydroxy-5-(trifluoromethoxy)acetophenone, 4-trifluoromethoxy-2-acetylphenol
| Molecular Formula | C9H7F3O3 |
|---|---|
| Molecular Weight | 220.03 g/mol |
| LogP | 2.4934 |
| Topological Polar Surface Area | 46.53 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 220.03473 |
| Heavy Atoms | 15 |
| Complexity | 384.67923 |
Chemical Identifiers
| CAS Number | 146575-64-6 |
|---|---|
| SMILES | CC(=O)C1=C(C=CC(=C1)OC(F)(F)F)O |
Product Overview
2'-Hydroxy-5'-(trifluoromethoxy)acetophenone (CAS 146575-64-6), with molecular formula C9H7F3O3 and molecular weight 220.03 g/mol. IUPAC: 1-[2-hydroxy-5-(trifluoromethoxy)phenyl]ethanone.
Chemical Property Profile of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone
Property Insights of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone
The XLogP value of 2.4934 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone. With a topological polar surface area (TPSA) of 46.53 Ų, 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone?
The CAS number of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone is 146575-64-6.
What is the molecular formula of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone?
The molecular formula of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone is C9H7F3O3.
What is the molecular weight of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone?
The molecular weight of 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone is 220.03 g/mol.
Where can I buy 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone?
You can request a quote for 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone?
Yes, KEHONG BIO provides custom synthesis services for 2'-Hydroxy-5'-(trifluoromethoxy)acetophenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.