Bromofosfamide
TL;DR: Bromofosfamide (CAS 146452-36-0) is a chemical compound with molecular formula C7H15BrClN2O2P and molecular weight 303.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-bromoethyl)-3-(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine
Also Known As: Bromofosfamide, KM 135, 2-thiophen-2-yl ethyl bromide, EX-A13928, N,N'-bis-(2-bromoethyl)phosphorodiamidic acid
| Molecular Formula | C7H15BrClN2O2P |
|---|---|
| Molecular Weight | 303.97 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 41.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 303.9743 |
| Heavy Atoms | 14 |
| Complexity | 220.0 |
Chemical Identifiers
| CAS Number | 146452-36-0 |
|---|---|
| SMILES | C1CN(P(=O)(OC1)NCCBr)CCCl |
| InChIKey | ZJVAVRRLTFVZIP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Bromofosfamide (CAS 146452-36-0), with molecular formula C7H15BrClN2O2P and molecular weight 303.97 g/mol. IUPAC: N-(2-bromoethyl)-3-(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine.
Chemical Property Profile of Bromofosfamide
Property Insights of Bromofosfamide
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bromofosfamide. With a topological polar surface area (TPSA) of 41.6 Ų, Bromofosfamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bromofosfamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bromofosfamide?
The CAS number of Bromofosfamide is 146452-36-0.
What is the molecular formula of Bromofosfamide?
The molecular formula of Bromofosfamide is C7H15BrClN2O2P.
What is the molecular weight of Bromofosfamide?
The molecular weight of Bromofosfamide is 303.97 g/mol.
Where can I buy Bromofosfamide?
You can request a quote for Bromofosfamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bromofosfamide?
Yes, KEHONG BIO provides custom synthesis services for Bromofosfamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.