5-(Pyridin-4-YL)-1H-imidazole-2-thiol
TL;DR: 5-(Pyridin-4-YL)-1H-imidazole-2-thiol (CAS 146366-04-3) is a chemical compound with molecular formula C8H7N3S and molecular weight 177.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-pyridin-4-yl-1,3-dihydroimidazole-2-thione
Also Known As: 5-(PYRIDIN-4-YL)-1H-IMIDAZOLE-2-THIOL, SB379278A, 4-pyridin-4-yl-1,3-dihydroimidazole-2-thione, AM751, SB-379278A
| Molecular Formula | C8H7N3S |
|---|---|
| Molecular Weight | 177.04 g/mol |
| LogP | 2.13429 |
| Topological Polar Surface Area | 44.47 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 177.03607 |
| Heavy Atoms | 12 |
| Complexity | 415.12296 |
Chemical Identifiers
| CAS Number | 146366-04-3 |
|---|---|
| SMILES | C1=CN=CC=C1C2=CNC(=S)N2 |
Product Overview
5-(Pyridin-4-YL)-1H-imidazole-2-thiol (CAS 146366-04-3), with molecular formula C8H7N3S and molecular weight 177.04 g/mol. IUPAC: 4-pyridin-4-yl-1,3-dihydroimidazole-2-thione.
Chemical Property Profile of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol
Property Insights of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol
The XLogP value of 2.13429 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(Pyridin-4-YL)-1H-imidazole-2-thiol. With a topological polar surface area (TPSA) of 44.47 Ų, 5-(Pyridin-4-YL)-1H-imidazole-2-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(Pyridin-4-YL)-1H-imidazole-2-thiol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol?
The CAS number of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol is 146366-04-3.
What is the molecular formula of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol?
The molecular formula of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol is C8H7N3S.
What is the molecular weight of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol?
The molecular weight of 5-(Pyridin-4-YL)-1H-imidazole-2-thiol is 177.04 g/mol.
Where can I buy 5-(Pyridin-4-YL)-1H-imidazole-2-thiol?
You can request a quote for 5-(Pyridin-4-YL)-1H-imidazole-2-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(Pyridin-4-YL)-1H-imidazole-2-thiol?
Yes, KEHONG BIO provides custom synthesis services for 5-(Pyridin-4-YL)-1H-imidazole-2-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.