Dexamethasone EP Impurity I
TL;DR: Dexamethasone EP Impurity I (CAS 14622-47-0) is a chemical compound with molecular formula C22H28O5 and molecular weight 372.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,2S,10S,11S,13R,14R,15S,17R)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one
Also Known As: Dexamethasone EP Impurity I, Dexamethasone Impurity I, Dexamethasone Impurity 1, Dexamethasone impurity I [EP], 16alpha-methyl epoxide(db-11)
| Molecular Formula | C22H28O5 |
|---|---|
| Molecular Weight | 372.19 g/mol |
| LogP | 1.9641 |
| Topological Polar Surface Area | 87.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 372.19366 |
| Heavy Atoms | 27 |
| Complexity | 813.52075 |
Chemical Identifiers
| CAS Number | 14622-47-0 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@@]35[C@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C |
Product Overview
Dexamethasone EP Impurity I (CAS 14622-47-0), with molecular formula C22H28O5 and molecular weight 372.19 g/mol. IUPAC: (1R,2S,10S,11S,13R,14R,15S,17R)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one.
Chemical Property Profile of Dexamethasone EP Impurity I
Property Insights of Dexamethasone EP Impurity I
The XLogP value of 1.9641 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dexamethasone EP Impurity I. The TPSA of 87.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Dexamethasone EP Impurity I. Following Lipinski's Rule of Five, Dexamethasone EP Impurity I has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dexamethasone EP Impurity I?
The CAS number of Dexamethasone EP Impurity I is 14622-47-0.
What is the molecular formula of Dexamethasone EP Impurity I?
The molecular formula of Dexamethasone EP Impurity I is C22H28O5.
What is the molecular weight of Dexamethasone EP Impurity I?
The molecular weight of Dexamethasone EP Impurity I is 372.19 g/mol.
Where can I buy Dexamethasone EP Impurity I?
You can request a quote for Dexamethasone EP Impurity I directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dexamethasone EP Impurity I?
Yes, KEHONG BIO provides custom synthesis services for Dexamethasone EP Impurity I and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.