2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline
TL;DR: 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline (CAS 146137-78-2) is a chemical compound with molecular formula C12H15F3N2 and molecular weight 244.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-piperidin-1-yl-5-(trifluoromethyl)aniline
Also Known As: 2-(piperidin-1-yl)-5-(trifluoromethyl)aniline, N-(2-Amino-4-trifluoromethylphenyl)piperidine, asischem z43511, akos bb-8562, Maybridge1_000752
| Molecular Formula | C12H15F3N2 |
|---|---|
| Molecular Weight | 244.12 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 29.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.11873 |
| Heavy Atoms | 17 |
| Complexity | 249.0 |
Chemical Identifiers
| CAS Number | 146137-78-2 |
|---|---|
| SMILES | C1CCN(CC1)C2=C(C=C(C=C2)C(F)(F)F)N |
| InChIKey | BERRRZOJDANPHE-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline (CAS 146137-78-2), with molecular formula C12H15F3N2 and molecular weight 244.12 g/mol. IUPAC: 2-piperidin-1-yl-5-(trifluoromethyl)aniline.
Chemical Property Profile of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline
Property Insights of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline
The XLogP value of 3.1 indicates that 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.3 Ų, 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline?
The CAS number of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline is 146137-78-2.
What is the molecular formula of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline?
The molecular formula of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline is C12H15F3N2.
What is the molecular weight of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline?
The molecular weight of 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline is 244.12 g/mol.
Where can I buy 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline?
You can request a quote for 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline?
Yes, KEHONG BIO provides custom synthesis services for 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.