2-(p-Cyanophenyl)-5-chlorobenzimidazole structure

2-(p-Cyanophenyl)-5-chlorobenzimidazole

TL;DR: 2-(p-Cyanophenyl)-5-chlorobenzimidazole (CAS 146132-86-7) is a chemical compound with molecular formula C14H8ClN3 and molecular weight 253.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(6-chloro-1H-benzimidazol-2-yl)benzonitrile

Also Known As: 4- BENZONITRILE, 2-[p-Cyanophenyl]-5-chlorobenzimidazole, 4-(6-chloro-1H-benzimidazol-2-yl)benzonitrile, 2-(p-Cyanophenyl)-5-chlorobenzimidazole, NCI60_019803

CAS: 146132-86-7
Molecular Formula C14H8ClN3
Molecular Weight 253.04 g/mol
LogP 3.6
Topological Polar Surface Area 52.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 253.04068
Heavy Atoms 18
Complexity 342.0

Chemical Identifiers

CAS Number 146132-86-7
SMILES C1=CC(=CC=C1C#N)C2=NC3=C(N2)C=C(C=C3)Cl
InChIKey UTADKFJRRZDHFW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (13 patents)

Product Overview

2-(p-Cyanophenyl)-5-chlorobenzimidazole (CAS 146132-86-7), with molecular formula C14H8ClN3 and molecular weight 253.04 g/mol. IUPAC: 4-(6-chloro-1H-benzimidazol-2-yl)benzonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2-(p-Cyanophenyl)-5-chlorobenzimidazole

XLogP
3.6
TPSA (Topological Polar Surface Area)
52.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
18
Complexity
342.0
Exact Mass
253.04068
Monoisotopic Mass
253.04068
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(p-Cyanophenyl)-5-chlorobenzimidazole

The XLogP value of 3.6 indicates that 2-(p-Cyanophenyl)-5-chlorobenzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.5 Ų, 2-(p-Cyanophenyl)-5-chlorobenzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(p-Cyanophenyl)-5-chlorobenzimidazole has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(p-Cyanophenyl)-5-chlorobenzimidazole?

The CAS number of 2-(p-Cyanophenyl)-5-chlorobenzimidazole is 146132-86-7.

What is the molecular formula of 2-(p-Cyanophenyl)-5-chlorobenzimidazole?

The molecular formula of 2-(p-Cyanophenyl)-5-chlorobenzimidazole is C14H8ClN3.

What is the molecular weight of 2-(p-Cyanophenyl)-5-chlorobenzimidazole?

The molecular weight of 2-(p-Cyanophenyl)-5-chlorobenzimidazole is 253.04 g/mol.

Where can I buy 2-(p-Cyanophenyl)-5-chlorobenzimidazole?

You can request a quote for 2-(p-Cyanophenyl)-5-chlorobenzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(p-Cyanophenyl)-5-chlorobenzimidazole?

Yes, KEHONG BIO provides custom synthesis services for 2-(p-Cyanophenyl)-5-chlorobenzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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