阿維莫泮
TL;DR: 阿維莫泮 (CAS 145590-44-9) is a chemical compound with molecular formula C25H32N2O4 and molecular weight 424.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
阿維莫泮
2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid
Also Known As: Alvimopan, Entereg, Alvimopan anhydrous, anhydrous alvimopan, alvimopanum
| Molecular Formula | C25H32N2O4 |
|---|---|
| Molecular Weight | 424.24 g/mol |
| LogP | 3.0514 |
| Topological Polar Surface Area | 89.87 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 424.2362 |
| Heavy Atoms | 31 |
| Complexity | 901.40485 |
Chemical Identifiers
| CAS Number | 145590-44-9 |
|---|---|
| SMILES | C[C@H]1CN(CC[C@@]1(C)C2=CC(=CC=C2)O)C[C@H](CC3=CC=CC=C3)C(=O)NCC(=O)O |
Product Overview
阿維莫泮 (CAS 145590-44-9), with molecular formula C25H32N2O4 and molecular weight 424.24 g/mol. IUPAC: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid.
Chemical Property Profile of 阿維莫泮
Property Insights of 阿維莫泮
The XLogP value of 3.0514 indicates that 阿維莫泮 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.87 Ų falls within the moderate polarity range, balancing permeability and solubility for 阿維莫泮. Following Lipinski's Rule of Five, 阿維莫泮 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 阿維莫泮?
The CAS number of 阿維莫泮 is 145590-44-9.
What is the molecular formula of 阿維莫泮?
The molecular formula of 阿維莫泮 is C25H32N2O4.
What is the molecular weight of 阿維莫泮?
The molecular weight of 阿維莫泮 is 424.24 g/mol.
Where can I buy 阿維莫泮?
You can request a quote for 阿維莫泮 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 阿維莫泮?
Yes, KEHONG BIO provides custom synthesis services for 阿維莫泮 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.