Icopezil
TL;DR: Icopezil (CAS 145508-78-7) is a chemical compound with molecular formula C23H25N3O2 and molecular weight 375.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[2-(1-benzylpiperidin-4-yl)ethyl]-5,7-dihydropyrrolo[3,2-f][1,2]benzoxazol-6-one
Also Known As: Icopezil, Icopezil [INN], icopezilo, Icopezil maleate, icopezilum
| Molecular Formula | C23H25N3O2 |
|---|---|
| Molecular Weight | 375.19 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 58.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 375.19467 |
| Heavy Atoms | 28 |
| Complexity | 542.0 |
Chemical Identifiers
| CAS Number | 145508-78-7 |
|---|---|
| SMILES | C1CN(CCC1CCC2=NOC3=C2C=C4CC(=O)NC4=C3)CC5=CC=CC=C5 |
| InChIKey | MTCMTKNMZCPKLX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Icopezil (CAS 145508-78-7), with molecular formula C23H25N3O2 and molecular weight 375.19 g/mol. IUPAC: 3-[2-(1-benzylpiperidin-4-yl)ethyl]-5,7-dihydropyrrolo[3,2-f][1,2]benzoxazol-6-one.
Chemical Property Profile of Icopezil
Property Insights of Icopezil
The XLogP value of 3.5 indicates that Icopezil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.4 Ų, Icopezil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Icopezil has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Icopezil?
The CAS number of Icopezil is 145508-78-7.
What is the molecular formula of Icopezil?
The molecular formula of Icopezil is C23H25N3O2.
What is the molecular weight of Icopezil?
The molecular weight of Icopezil is 375.19 g/mol.
Where can I buy Icopezil?
You can request a quote for Icopezil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Icopezil?
Yes, KEHONG BIO provides custom synthesis services for Icopezil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.