N-Despropyl Gamithromycin
TL;DR: N-Despropyl Gamithromycin (CAS 145388-07-4) is a chemical compound with molecular formula C37H70N2O12 and molecular weight 734.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-7-azacyclopentadecan-15-one
Also Known As: N-Despropyl Gamithromycin, Azithromycin Impurity 50, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-7-azacyclopentadecan-15-one, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-
| Molecular Formula | C37H70N2O12 |
|---|---|
| Molecular Weight | 734.49 g/mol |
| LogP | 1.5585 |
| Topological Polar Surface Area | 188.87 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 7 |
| Exact Mass | 734.49286 |
| Heavy Atoms | 51 |
| Complexity | 1111.4337 |
Chemical Identifiers
| CAS Number | 145388-07-4 |
|---|---|
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](CN[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O |
Product Overview
N-Despropyl Gamithromycin (CAS 145388-07-4), with molecular formula C37H70N2O12 and molecular weight 734.49 g/mol. IUPAC: (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-7-azacyclopentadecan-15-one.
Chemical Property Profile of N-Despropyl Gamithromycin
Property Insights of N-Despropyl Gamithromycin
The XLogP value of 1.5585 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Despropyl Gamithromycin. The TPSA of 188.87 Ų indicates high polarity, suggesting N-Despropyl Gamithromycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-Despropyl Gamithromycin has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Despropyl Gamithromycin?
The CAS number of N-Despropyl Gamithromycin is 145388-07-4.
What is the molecular formula of N-Despropyl Gamithromycin?
The molecular formula of N-Despropyl Gamithromycin is C37H70N2O12.
What is the molecular weight of N-Despropyl Gamithromycin?
The molecular weight of N-Despropyl Gamithromycin is 734.49 g/mol.
Where can I buy N-Despropyl Gamithromycin?
You can request a quote for N-Despropyl Gamithromycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Despropyl Gamithromycin?
Yes, KEHONG BIO provides custom synthesis services for N-Despropyl Gamithromycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.