米格列奈
TL;DR: 米格列奈 (CAS 145375-43-5) is a chemical compound with molecular formula C19H25NO3 and molecular weight 315.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
米格列奈
(2S)-4-[(3aR,7aS)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoic acid
Also Known As: Mitiglinide, mitiglinida, mitiglinidum, Glufast, miti-glinide
| Molecular Formula | C19H25NO3 |
|---|---|
| Molecular Weight | 315.18 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 57.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 315.18344 |
| Heavy Atoms | 23 |
| Complexity | 416.0 |
Chemical Identifiers
| CAS Number | 145375-43-5 |
|---|---|
| SMILES | C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)O |
| InChIKey | WPGGHFDDFPHPOB-BBWFWOEESA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
米格列奈 (CAS 145375-43-5), with molecular formula C19H25NO3 and molecular weight 315.18 g/mol. IUPAC: (2S)-4-[(3aR,7aS)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoic acid.
Chemical Property Profile of 米格列奈
Property Insights of 米格列奈
The XLogP value of 3.0 indicates that 米格列奈 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.6 Ų, 米格列奈 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 米格列奈 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 米格列奈?
The CAS number of 米格列奈 is 145375-43-5.
What is the molecular formula of 米格列奈?
The molecular formula of 米格列奈 is C19H25NO3.
What is the molecular weight of 米格列奈?
The molecular weight of 米格列奈 is 315.18 g/mol.
Where can I buy 米格列奈?
You can request a quote for 米格列奈 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 米格列奈?
Yes, KEHONG BIO provides custom synthesis services for 米格列奈 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.