Erythromycin A 6,10-Imino Ether
TL;DR: Erythromycin A 6,10-Imino Ether (CAS 145259-56-9) is a chemical compound with molecular formula C37H66N2O12 and molecular weight 730.46 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-ethyl-3,4-dihydroxy-9-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,8,10,12,14-hexamethyl-6,16-dioxa-15-azabicyclo[10.3.1]hexadec-1(15)-en-7-one
Also Known As: Azithromycin Impurity 61, Erythromycin A 6,10-Imino Ether, 6-O,9-Cyclo-8a,9-didehydro-9-deoxo-8a-aza-8a-homoerythromycin, (2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-ethyl-3,4-dihydroxy-9-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,4,8,10,12,14-hexamethyl-6,16-dioxa-15-azabicyclo[10.3.1]hexadec-1(15)-en-7-one, (2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-5-ethyl-3,4-dihydroxy-9-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-2,4,8,10,12,14-hexamethyl-6,16-dioxa-15-azabicyclo[10.3.1]hexadec-1(15)-en-7-one
| Molecular Formula | C37H66N2O12 |
|---|---|
| Molecular Weight | 730.46 g/mol |
| LogP | 2.4053 |
| Topological Polar Surface Area | 178.2 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 7 |
| Exact Mass | 730.46155 |
| Heavy Atoms | 51 |
| Complexity | 1219.943 |
Chemical Identifiers
| CAS Number | 145259-56-9 |
|---|---|
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C2=N[C@@H](C[C@@](O2)([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)C)C)C)O)(C)O |
Product Overview
Erythromycin A 6,10-Imino Ether (CAS 145259-56-9), with molecular formula C37H66N2O12 and molecular weight 730.46 g/mol. IUPAC: (2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-ethyl-3,4-dihydroxy-9-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,8,10,12,14-hexamethyl-6,16-dioxa-15-azabicyclo[10.3.1]hexadec-1(15)-en-7-one.
Chemical Property Profile of Erythromycin A 6,10-Imino Ether
Property Insights of Erythromycin A 6,10-Imino Ether
The XLogP value of 2.4053 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Erythromycin A 6,10-Imino Ether. The TPSA of 178.2 Ų indicates high polarity, suggesting Erythromycin A 6,10-Imino Ether may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Erythromycin A 6,10-Imino Ether has 4 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Erythromycin A 6,10-Imino Ether?
The CAS number of Erythromycin A 6,10-Imino Ether is 145259-56-9.
What is the molecular formula of Erythromycin A 6,10-Imino Ether?
The molecular formula of Erythromycin A 6,10-Imino Ether is C37H66N2O12.
What is the molecular weight of Erythromycin A 6,10-Imino Ether?
The molecular weight of Erythromycin A 6,10-Imino Ether is 730.46 g/mol.
Where can I buy Erythromycin A 6,10-Imino Ether?
You can request a quote for Erythromycin A 6,10-Imino Ether directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Erythromycin A 6,10-Imino Ether?
Yes, KEHONG BIO provides custom synthesis services for Erythromycin A 6,10-Imino Ether and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.