Met-His structure

Met-His

TL;DR: Met-His (CAS 14486-12-5) is a chemical compound with molecular formula C11H18N4O3S and molecular weight 286.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid

Also Known As: H-Met-His-OH, Met-His, Methionyl-Histidine, L-methionyl-L-histidine, MH peptide

CAS: 14486-12-5
Molecular Formula C11H18N4O3S
Molecular Weight 286.11 g/mol
LogP -0.398
Topological Polar Surface Area 121.1 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 5
Rotatable Bonds 8
Exact Mass 286.10995
Heavy Atoms 19
Complexity 410.0826

Chemical Identifiers

CAS Number 14486-12-5
SMILES CSCC[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)O)N

Product Overview

Met-His (CAS 14486-12-5), with molecular formula C11H18N4O3S and molecular weight 286.11 g/mol. IUPAC: (2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Met-His

XLogP
-0.398
TPSA (Topological Polar Surface Area)
121.1
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
5
Rotatable Bonds
8
Heavy Atoms
19
Complexity
410.0826
Exact Mass
286.10995
Monoisotopic Mass
286.10995
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Met-His

The XLogP value of -0.398 indicates that Met-His is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 121.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Met-His. Following Lipinski's Rule of Five, Met-His has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Met-His?

The CAS number of Met-His is 14486-12-5.

What is the molecular formula of Met-His?

The molecular formula of Met-His is C11H18N4O3S.

What is the molecular weight of Met-His?

The molecular weight of Met-His is 286.11 g/mol.

Where can I buy Met-His?

You can request a quote for Met-His directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Met-His?

Yes, KEHONG BIO provides custom synthesis services for Met-His and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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