替米沙坦
TL;DR: 替米沙坦 (CAS 144701-48-4) is a chemical compound with molecular formula C33H30N4O2 and molecular weight 514.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
替米沙坦
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
Also Known As: Telmisartan, Micardis, Pritor, Kinzalmono, Semintra
| Molecular Formula | C33H30N4O2 |
|---|---|
| Molecular Weight | 514.24 g/mol |
| LogP | 6.9 |
| Topological Polar Surface Area | 72.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 514.2369 |
| Heavy Atoms | 39 |
| Complexity | 831.0 |
| Melting Point | 261-263 °C |
| Solubility | Practically insoluble |
Chemical Identifiers
| CAS Number | 144701-48-4 |
|---|---|
| SMILES | CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C |
| InChIKey | RMMXLENWKUUMAY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
替米沙坦 (CAS 144701-48-4), with molecular formula C33H30N4O2 and molecular weight 514.24 g/mol. IUPAC: 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid.
Chemical Property Profile of 替米沙坦
Property Insights of 替米沙坦
The XLogP value of 6.9 indicates that 替米沙坦 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 替米沙坦. Following Lipinski's Rule of Five, 替米沙坦 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 替米沙坦?
The CAS number of 替米沙坦 is 144701-48-4.
What is the molecular formula of 替米沙坦?
The molecular formula of 替米沙坦 is C33H30N4O2.
What is the molecular weight of 替米沙坦?
The molecular weight of 替米沙坦 is 514.24 g/mol.
Where can I buy 替米沙坦?
You can request a quote for 替米沙坦 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 替米沙坦?
Yes, KEHONG BIO provides custom synthesis services for 替米沙坦 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.