Pixantrone dimaleate structure

Pixantrone dimaleate

TL;DR: Pixantrone dimaleate (CAS 144675-97-8) is a chemical compound with molecular formula C25H27N5O10 and molecular weight 557.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione;bis(but-2-enedioic acid)

Also Known As: Pixantrone dimaleate, Pixantrone maleate, Pixolti, Pixuvri, Pixantrone dimaleate [USAN]

CAS: 144675-97-8
Molecular Formula C25H27N5O10
Molecular Weight 557.18 g/mol
LogP 0.0218
Topological Polar Surface Area 272.33 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 11
Rotatable Bonds 10
Exact Mass 557.1758
Heavy Atoms 40
Complexity 1205.2654

Chemical Identifiers

CAS Number 144675-97-8
SMILES C1=CC(=C2C(=C1NCCN)C(=O)C3=C(C2=O)C=NC=C3)NCCN.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Product Overview

Pixantrone dimaleate (CAS 144675-97-8), with molecular formula C25H27N5O10 and molecular weight 557.18 g/mol. IUPAC: 6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione;bis(but-2-enedioic acid).

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pixantrone dimaleate

XLogP
0.0218
TPSA (Topological Polar Surface Area)
272.33
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
11
Rotatable Bonds
10
Heavy Atoms
40
Complexity
1205.2654
Exact Mass
557.1758
Monoisotopic Mass
557.1758
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pixantrone dimaleate

The XLogP value of 0.0218 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Pixantrone dimaleate. The TPSA of 272.33 Ų indicates high polarity, suggesting Pixantrone dimaleate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pixantrone dimaleate has 8 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pixantrone dimaleate?

The CAS number of Pixantrone dimaleate is 144675-97-8.

What is the molecular formula of Pixantrone dimaleate?

The molecular formula of Pixantrone dimaleate is C25H27N5O10.

What is the molecular weight of Pixantrone dimaleate?

The molecular weight of Pixantrone dimaleate is 557.18 g/mol.

Where can I buy Pixantrone dimaleate?

You can request a quote for Pixantrone dimaleate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pixantrone dimaleate?

Yes, KEHONG BIO provides custom synthesis services for Pixantrone dimaleate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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