Cob(III)alamin structure

Cob(III)alamin

TL;DR: Cob(III)alamin (CAS 14463-33-3) is a chemical compound with molecular formula C62H88CoN13O14P-2 and molecular weight 1328.56 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

cobalt;[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate

Also Known As: Cob(II)alamin, cobalamin, Cob(III)alamin, Cobalamine, Hydroxomin

CAS: 14463-33-3
Molecular Formula C62H88CoN13O14P-2
Molecular Weight 1328.56 g/mol
LogP 3.31284
Topological Polar Surface Area 464.92 Ų
Hydrogen Bond Donors 9
Hydrogen Bond Acceptors 18
Rotatable Bonds 26
Exact Mass 1328.5643
Heavy Atoms 91
Complexity 3544.1829

Chemical Identifiers

CAS Number 14463-33-3
SMILES CC1=CC2=C(C=C1C)N(C=N2)[C@@H]3[C@@H]([C@@H]([C@H](O3)CO)OP(=O)([O-])O[C@H](C)CNC(=O)CC[C@@]\4([C@H]([C@@H]5[C@]6([C@@]([C@@H](C(=N6)/C(=C\7/[C@@]([C@@H](C(=N7)/C=C\8/C([C@@H](C(=N8)/C(=C4\[N-]5)/C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)/C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[Co]

Product Overview

Cob(III)alamin (CAS 14463-33-3), with molecular formula C62H88CoN13O14P-2 and molecular weight 1328.56 g/mol. IUPAC: cobalt;[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Cob(III)alamin

XLogP
3.31284
TPSA (Topological Polar Surface Area)
464.92
Hydrogen Bond Donors
9
Hydrogen Bond Acceptors
18
Rotatable Bonds
26
Heavy Atoms
91
Complexity
3544.1829
Exact Mass
1328.5643
Monoisotopic Mass
1328.5643
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cob(III)alamin

The XLogP value of 3.31284 indicates that Cob(III)alamin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 464.92 Ų indicates high polarity, suggesting Cob(III)alamin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Cob(III)alamin has 9 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cob(III)alamin?

The CAS number of Cob(III)alamin is 14463-33-3.

What is the molecular formula of Cob(III)alamin?

The molecular formula of Cob(III)alamin is C62H88CoN13O14P-2.

What is the molecular weight of Cob(III)alamin?

The molecular weight of Cob(III)alamin is 1328.56 g/mol.

Where can I buy Cob(III)alamin?

You can request a quote for Cob(III)alamin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cob(III)alamin?

Yes, KEHONG BIO provides custom synthesis services for Cob(III)alamin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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