3-Hydroxycholest-8(14),24-dien-15-one
TL;DR: 3-Hydroxycholest-8(14),24-dien-15-one (CAS 144535-22-8) is a chemical compound with molecular formula C27H42O2 and molecular weight 398.32 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,5S,9R,10S,13R,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,4,5,6,7,9,11,12,16,17-dodecahydrocyclopenta[a]phenanthren-15-one
Also Known As: 3-Hac-8,24-dien-15-one, 3-Hydroxycholest-8(14),24-dien-15-one, 3-Hydroxycholesta-8(14),24-dien-15-one, 3beta-Hydroxy-5alpha-cholest-8(14),24-dien-15-one, 3beta-Hydroxy-5alpha-cholesta-8(14),24-dien-15-one
| Molecular Formula | C27H42O2 |
|---|---|
| Molecular Weight | 398.32 g/mol |
| LogP | 6.6 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 398.31848 |
| Heavy Atoms | 29 |
| Complexity | 727.0 |
Chemical Identifiers
| CAS Number | 144535-22-8 |
|---|---|
| SMILES | C[C@H](CCC=C(C)C)[C@H]1CC(=O)C2=C3CC[C@H]4C[C@H](CC[C@@]4([C@H]3CC[C@]12C)C)O |
| InChIKey | ZAQVWQHOVZZEEC-GGVPDPBRSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3-Hydroxycholest-8(14),24-dien-15-one (CAS 144535-22-8), with molecular formula C27H42O2 and molecular weight 398.32 g/mol. IUPAC: (3S,5S,9R,10S,13R,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,4,5,6,7,9,11,12,16,17-dodecahydrocyclopenta[a]phenanthren-15-one.
Chemical Property Profile of 3-Hydroxycholest-8(14),24-dien-15-one
Property Insights of 3-Hydroxycholest-8(14),24-dien-15-one
The XLogP value of 6.6 indicates that 3-Hydroxycholest-8(14),24-dien-15-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 3-Hydroxycholest-8(14),24-dien-15-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxycholest-8(14),24-dien-15-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Hydroxycholest-8(14),24-dien-15-one?
The CAS number of 3-Hydroxycholest-8(14),24-dien-15-one is 144535-22-8.
What is the molecular formula of 3-Hydroxycholest-8(14),24-dien-15-one?
The molecular formula of 3-Hydroxycholest-8(14),24-dien-15-one is C27H42O2.
What is the molecular weight of 3-Hydroxycholest-8(14),24-dien-15-one?
The molecular weight of 3-Hydroxycholest-8(14),24-dien-15-one is 398.32 g/mol.
Where can I buy 3-Hydroxycholest-8(14),24-dien-15-one?
You can request a quote for 3-Hydroxycholest-8(14),24-dien-15-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Hydroxycholest-8(14),24-dien-15-one?
Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxycholest-8(14),24-dien-15-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.