GR 92549
TL;DR: GR 92549 (CAS 144501-27-9) is a chemical compound with molecular formula C25H26F2N2O4 and molecular weight 456.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E,3S,5R)-7-[4,5-bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid
Also Known As: GR 92549, GR95030X, 3,5-Dihydroxy-7-(4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazol-1-yl)-6-heptenoic acid, (E,3S,5R)-7-[4,5-bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid, (3S,5R,6E)-7-[4,5-bis(4-fluorophenyl)-2-(propan-2-yl)-1H-imidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid
| Molecular Formula | C25H26F2N2O4 |
|---|---|
| Molecular Weight | 456.19 g/mol |
| LogP | 4.676 |
| Topological Polar Surface Area | 95.58 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 9 |
| Exact Mass | 456.18607 |
| Heavy Atoms | 33 |
| Complexity | 1122.5587 |
Chemical Identifiers
| CAS Number | 144501-27-9 |
|---|---|
| SMILES | CC(C)C1=NC(=C(N1/C=C/[C@@H](C[C@@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
Product Overview
GR 92549 (CAS 144501-27-9), with molecular formula C25H26F2N2O4 and molecular weight 456.19 g/mol. IUPAC: (E,3S,5R)-7-[4,5-bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid.
Chemical Property Profile of GR 92549
Property Insights of GR 92549
The XLogP value of 4.676 indicates that GR 92549 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.58 Ų falls within the moderate polarity range, balancing permeability and solubility for GR 92549. Following Lipinski's Rule of Five, GR 92549 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GR 92549?
The CAS number of GR 92549 is 144501-27-9.
What is the molecular formula of GR 92549?
The molecular formula of GR 92549 is C25H26F2N2O4.
What is the molecular weight of GR 92549?
The molecular weight of GR 92549 is 456.19 g/mol.
Where can I buy GR 92549?
You can request a quote for GR 92549 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GR 92549?
Yes, KEHONG BIO provides custom synthesis services for GR 92549 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.