19-Epi FK-506
TL;DR: 19-Epi FK-506 (CAS 144490-63-1) is a chemical compound with molecular formula C44H69NO12 and molecular weight 803.48 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(18Z)-1,14-dihydroxy-12-[(E)-1-(4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Also Known As: 19-Epi FK-506, I06-0080
| Molecular Formula | C44H69NO12 |
|---|---|
| Molecular Weight | 803.48 g/mol |
| LogP | 4.639 |
| Topological Polar Surface Area | 178.36 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 7 |
| Exact Mass | 803.482 |
| Heavy Atoms | 57 |
| Complexity | 1478.2959 |
Chemical Identifiers
| CAS Number | 144490-63-1 |
|---|---|
| SMILES | CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(/C=C(\C1)/C)CC=C)O)C)/C(=C/C4CCC(C(C4)OC)O)/C)O)C)OC)OC |
Product Overview
19-Epi FK-506 (CAS 144490-63-1), with molecular formula C44H69NO12 and molecular weight 803.48 g/mol. IUPAC: (18Z)-1,14-dihydroxy-12-[(E)-1-(4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone.
Chemical Property Profile of 19-Epi FK-506
Property Insights of 19-Epi FK-506
The XLogP value of 4.639 indicates that 19-Epi FK-506 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 178.36 Ų indicates high polarity, suggesting 19-Epi FK-506 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 19-Epi FK-506 has 3 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 19-Epi FK-506?
The CAS number of 19-Epi FK-506 is 144490-63-1.
What is the molecular formula of 19-Epi FK-506?
The molecular formula of 19-Epi FK-506 is C44H69NO12.
What is the molecular weight of 19-Epi FK-506?
The molecular weight of 19-Epi FK-506 is 803.48 g/mol.
Where can I buy 19-Epi FK-506?
You can request a quote for 19-Epi FK-506 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 19-Epi FK-506?
Yes, KEHONG BIO provides custom synthesis services for 19-Epi FK-506 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.