4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione
TL;DR: 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione (CAS 144464-20-0) is a chemical compound with molecular formula C17H14N4S2 and molecular weight 338.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2-thione
Also Known As: 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione, AS-871/41492788, 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2-thione, 3-(4-Methylphenyl)-4-amino-5-(1H-benzimidazol-2-yl)thiazole-2(3H)-thione, 4-amino-5-(1H-benzoimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2-thione
| Molecular Formula | C17H14N4S2 |
|---|---|
| Molecular Weight | 338.07 g/mol |
| LogP | 4.70221 |
| Topological Polar Surface Area | 59.63 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 338.06598 |
| Heavy Atoms | 23 |
| Complexity | 1021.3345 |
Chemical Identifiers
| CAS Number | 144464-20-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(=C(SC2=S)C3=NC4=CC=CC=C4N3)N |
Product Overview
4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione (CAS 144464-20-0), with molecular formula C17H14N4S2 and molecular weight 338.07 g/mol. IUPAC: 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2-thione.
Chemical Property Profile of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione
Property Insights of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione
The XLogP value of 4.70221 indicates that 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.63 Ų, 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione?
The CAS number of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione is 144464-20-0.
What is the molecular formula of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione?
The molecular formula of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione is C17H14N4S2.
What is the molecular weight of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione?
The molecular weight of 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione is 338.07 g/mol.
Where can I buy 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione?
You can request a quote for 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-amino-5-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)-1,3-thiazole-2(3H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.