EGIS-9377 free base
TL;DR: EGIS-9377 free base (CAS 144430-52-4) is a chemical compound with molecular formula C15H22N6OS2 and molecular weight 366.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methylsulfanyl-N-(2-morpholin-4-ylethyl)-10-thia-2,4,6,7-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraen-8-amine
Also Known As: EGIS-9377 free base, J1.253.361F, 7H-Thiopyrano(3,2-d)(1,2,4)triazolo(1,5-a)pyrimidin-5-amine, 8,9-dihydro-2-(methylthio)-N-(2-(4-morpholinyl)ethyl)-, 2-(Methylthio)-5-[[2-(morpholino)ethyl]amino]-8,9-dihydro-7H-thiopyrano[3,2-d][1,2,4]triazolo[1,5-a]pyrimidine, 5-(methylsulfanyl)-N-[2-(morpholin-4-yl)ethyl]-10-thia-2,4,6,7-tetraazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraen-8-amine
| Molecular Formula | C15H22N6OS2 |
|---|---|
| Molecular Weight | 366.13 g/mol |
| LogP | 1.6286 |
| Topological Polar Surface Area | 67.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 366.12964 |
| Heavy Atoms | 24 |
| Complexity | 715.5425 |
Chemical Identifiers
| CAS Number | 144430-52-4 |
|---|---|
| SMILES | CSC1=NN2C(=C3C(=NC2=N1)CCCS3)NCCN4CCOCC4 |
Product Overview
EGIS-9377 free base (CAS 144430-52-4), with molecular formula C15H22N6OS2 and molecular weight 366.13 g/mol. IUPAC: 5-methylsulfanyl-N-(2-morpholin-4-ylethyl)-10-thia-2,4,6,7-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraen-8-amine.
Chemical Property Profile of EGIS-9377 free base
Property Insights of EGIS-9377 free base
The XLogP value of 1.6286 suggests moderate lipophilicity, balancing water solubility and membrane permeability for EGIS-9377 free base. The TPSA of 67.58 Ų falls within the moderate polarity range, balancing permeability and solubility for EGIS-9377 free base. Following Lipinski's Rule of Five, EGIS-9377 free base has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of EGIS-9377 free base?
The CAS number of EGIS-9377 free base is 144430-52-4.
What is the molecular formula of EGIS-9377 free base?
The molecular formula of EGIS-9377 free base is C15H22N6OS2.
What is the molecular weight of EGIS-9377 free base?
The molecular weight of EGIS-9377 free base is 366.13 g/mol.
Where can I buy EGIS-9377 free base?
You can request a quote for EGIS-9377 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for EGIS-9377 free base?
Yes, KEHONG BIO provides custom synthesis services for EGIS-9377 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.