MHDEA
TL;DR: MHDEA (CAS 144224-33-9) is a chemical compound with molecular formula C14H22N8O4 and molecular weight 366.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylamino]propanehydrazide
Also Known As: MHDEA, AdoMet substrate analogue, 17l, 5'-Deoxy-5'-[2-(hydrazinocarbonylethyl)methylamino]adenosine, 5 -[(3-Hydrazino-3-oxopropyl)methylamino]-5 -deoxyadenosine, Adenosine, 5'-deoxy-5'-[(3-hydrazino-3-oxopropyl)methylamino]-
| Molecular Formula | C14H22N8O4 |
|---|---|
| Molecular Weight | 366.18 g/mol |
| LogP | -2.4 |
| Topological Polar Surface Area | 178.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 6 |
| Exact Mass | 366.1764 |
| Heavy Atoms | 26 |
| Complexity | 500.0 |
Chemical Identifiers
| CAS Number | 144224-33-9 |
|---|---|
| SMILES | CN(CCC(=O)NN)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O |
| InChIKey | WKMJVKMHOKHLRE-FRJWGUMJSA-N |
Product Overview
MHDEA (CAS 144224-33-9), with molecular formula C14H22N8O4 and molecular weight 366.18 g/mol. IUPAC: 3-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylamino]propanehydrazide.
Chemical Property Profile of MHDEA
Property Insights of MHDEA
The XLogP value of -2.4 indicates that MHDEA is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 178.0 Ų indicates high polarity, suggesting MHDEA may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, MHDEA has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of MHDEA?
The CAS number of MHDEA is 144224-33-9.
What is the molecular formula of MHDEA?
The molecular formula of MHDEA is C14H22N8O4.
What is the molecular weight of MHDEA?
The molecular weight of MHDEA is 366.18 g/mol.
Where can I buy MHDEA?
You can request a quote for MHDEA directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for MHDEA?
Yes, KEHONG BIO provides custom synthesis services for MHDEA and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.