Estradiol-3,4-quinone structure

Estradiol-3,4-quinone

TL;DR: Estradiol-3,4-quinone (CAS 144082-88-2) is a chemical compound with molecular formula C18H22O3 and molecular weight 286.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,4-dione

Also Known As: Estradiol-3,4-quinone, 17beta-Estradiol-3,4-quinone, KST-1A1465, E2-3,4-Q, SID:53790643

CAS: 144082-88-2
Molecular Formula C18H22O3
Molecular Weight 286.16 g/mol
LogP 2.3
Topological Polar Surface Area 54.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 0
Exact Mass 286.1569
Heavy Atoms 21
Complexity 585.0

Chemical Identifiers

CAS Number 144082-88-2
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=O)C4=O
InChIKey XVPUMLOTNZVTSL-ZHIYBZGJSA-N

Product Overview

Estradiol-3,4-quinone (CAS 144082-88-2), with molecular formula C18H22O3 and molecular weight 286.16 g/mol. IUPAC: (8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Estradiol-3,4-quinone

XLogP
2.3
TPSA (Topological Polar Surface Area)
54.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
0
Heavy Atoms
21
Complexity
585.0
Exact Mass
286.1569
Monoisotopic Mass
286.1569
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Estradiol-3,4-quinone

The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Estradiol-3,4-quinone. With a topological polar surface area (TPSA) of 54.4 Ų, Estradiol-3,4-quinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Estradiol-3,4-quinone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Estradiol-3,4-quinone?

The CAS number of Estradiol-3,4-quinone is 144082-88-2.

What is the molecular formula of Estradiol-3,4-quinone?

The molecular formula of Estradiol-3,4-quinone is C18H22O3.

What is the molecular weight of Estradiol-3,4-quinone?

The molecular weight of Estradiol-3,4-quinone is 286.16 g/mol.

Where can I buy Estradiol-3,4-quinone?

You can request a quote for Estradiol-3,4-quinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Estradiol-3,4-quinone?

Yes, KEHONG BIO provides custom synthesis services for Estradiol-3,4-quinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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