TAPI (inhibitor)
TL;DR: TAPI (inhibitor) (CAS 143457-40-3) is a chemical compound with molecular formula C24H32N4O5 and molecular weight 456.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
Also Known As: TAPI (inhibitor), TAPI, TNF-alpha Protease Inhibitor-0, (S,S)-TAPI-0, EX-A2658
| Molecular Formula | C24H32N4O5 |
|---|---|
| Molecular Weight | 456.24 g/mol |
| LogP | 1.4149 |
| Topological Polar Surface Area | 150.62 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 11 |
| Exact Mass | 456.23727 |
| Heavy Atoms | 33 |
| Complexity | 1007.2671 |
Chemical Identifiers
| CAS Number | 143457-40-3 |
|---|---|
| SMILES | C[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)C(CC(C)C)CC(=O)NO |
Product Overview
TAPI (inhibitor) (CAS 143457-40-3), with molecular formula C24H32N4O5 and molecular weight 456.24 g/mol. IUPAC: N-[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide.
Chemical Property Profile of TAPI (inhibitor)
Property Insights of TAPI (inhibitor)
The XLogP value of 1.4149 suggests moderate lipophilicity, balancing water solubility and membrane permeability for TAPI (inhibitor). The TPSA of 150.62 Ų indicates high polarity, suggesting TAPI (inhibitor) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, TAPI (inhibitor) has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TAPI (inhibitor)?
The CAS number of TAPI (inhibitor) is 143457-40-3.
What is the molecular formula of TAPI (inhibitor)?
The molecular formula of TAPI (inhibitor) is C24H32N4O5.
What is the molecular weight of TAPI (inhibitor)?
The molecular weight of TAPI (inhibitor) is 456.24 g/mol.
Where can I buy TAPI (inhibitor)?
You can request a quote for TAPI (inhibitor) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TAPI (inhibitor)?
Yes, KEHONG BIO provides custom synthesis services for TAPI (inhibitor) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.