3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-
概要：3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-（CAS 143382-88-1）是一种化学化合物，分子式为C22H25F4N3O3，分子量为455.18 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
1-cyclopropyl-7-[(3R)-3-[(1S)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid
又称：3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-, (S-(R,S))-1-Cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid, 1-cyclopropyl-7-[(3R)-3-[(1S)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid, 1-Cyclopropyl-1,4-dihydro-8-(trifluoromethyl)-6-fluoro-7-[(3R)-3-[(S)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-7-[(3R)-3-[(1S)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid
| 分子式 | C22H25F4N3O3 |
|---|---|
| 分子量 | 455.18 g/mol |
| LogP | 4.0168 |
| 拓扑极性表面积 | 74.57 Ų |
| 氢键供体数 | 2 |
| 氢键受体数 | 4 |
| 可旋转键数 | 6 |
| 精确质量 | 455.1832 |
| 重原子数 | 32 |
| 复杂度 | 1124.3171 |
化学标识符
| CAS 编号 | 143382-88-1 |
|---|---|
| SMILES | CCN[C@@H](C)[C@@H]1CCN(C1)C2=C(C=C3C(=C2C(F)(F)F)N(C=C(C3=O)C(=O)O)C4CC4)F |
产品概述
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-（CAS 143382-88-1），分子式为C22H25F4N3O3，分子量为455.18 g/mol。IUPAC名：1-cyclopropyl-7-[(3R)-3-[(1S)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid。
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-化学性质概览
属性洞察：3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的XLogP值为4.0168，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为74.57 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-有2个氢键供体和4个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的CAS号是多少？
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的CAS号为143382-88-1。
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的分子式是什么？
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的分子式为C22H25F4N3O3。
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的分子量是多少？
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的分子量为455.18 g/mol。
在哪里可以购买3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-？
您可以直接向科弘生物询价3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-的定制合成服务？
是的，科弘生物提供3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-4-oxo-8-(trifluoromethyl)-, (S-(R*,S*))-及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。