![3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- structure](/static/products/1433/143382-87-0.webp)
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-
TL;DR: 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- (CAS 143382-87-0) is a chemical compound with molecular formula C22H25F4N3O3 and molecular weight 455.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-cyclopropyl-7-[(3R)-3-[(1R)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid
Also Known As: 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-, 1-cyclopropyl-7-[(3R)-3-[(1R)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid
| Molecular Formula | C22H25F4N3O3 |
|---|---|
| Molecular Weight | 455.18 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 72.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 6 |
| Exact Mass | 455.1832 |
| Heavy Atoms | 32 |
| Complexity | 785.0 |
Chemical Identifiers
| CAS Number | 143382-87-0 |
|---|---|
| SMILES | CCN[C@H](C)[C@@H]1CCN(C1)C2=C(C=C3C(=C2C(F)(F)F)N(C=C(C3=O)C(=O)O)C4CC4)F |
| InChIKey | KRRFNOYEJSQDRL-VXGBXAGGSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- (CAS 143382-87-0), with molecular formula C22H25F4N3O3 and molecular weight 455.18 g/mol. IUPAC: 1-cyclopropyl-7-[(3R)-3-[(1R)-1-(ethylamino)ethyl]pyrrolidin-1-yl]-6-fluoro-4-oxo-8-(trifluoromethyl)quinoline-3-carboxylic acid.
Chemical Property Profile of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-
Property Insights of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-. The TPSA of 72.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-. Following Lipinski's Rule of Five, 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-?
The CAS number of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- is 143382-87-0.
What is the molecular formula of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-?
The molecular formula of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- is C22H25F4N3O3.
What is the molecular weight of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-?
The molecular weight of 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- is 455.18 g/mol.
Where can I buy 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-?
You can request a quote for 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-?
Yes, KEHONG BIO provides custom synthesis services for 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.