7-Methoxy tropisetron
TL;DR: 7-Methoxy tropisetron (CAS 143207-25-4) is a chemical compound with molecular formula C18H22N2O3 and molecular weight 314.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 7-methoxy-1H-indole-3-carboxylate
Also Known As: 7-Methoxy tropisetron, SDZ-ICM-567 free base, SDZ-ICM-567, 1H-Indole-3-carboxylic acid, 7-methoxy-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 7-methoxy-1H-indole-3-carboxylate
| Molecular Formula | C18H22N2O3 |
|---|---|
| Molecular Weight | 314.16 g/mol |
| LogP | 2.9585 |
| Topological Polar Surface Area | 54.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 314.16306 |
| Heavy Atoms | 23 |
| Complexity | 724.94196 |
Chemical Identifiers
| CAS Number | 143207-25-4 |
|---|---|
| SMILES | CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C3=CNC4=C3C=CC=C4OC |
Product Overview
7-Methoxy tropisetron (CAS 143207-25-4), with molecular formula C18H22N2O3 and molecular weight 314.16 g/mol. IUPAC: [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 7-methoxy-1H-indole-3-carboxylate.
Chemical Property Profile of 7-Methoxy tropisetron
Property Insights of 7-Methoxy tropisetron
The XLogP value of 2.9585 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Methoxy tropisetron. With a topological polar surface area (TPSA) of 54.56 Ų, 7-Methoxy tropisetron exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-Methoxy tropisetron has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Methoxy tropisetron?
The CAS number of 7-Methoxy tropisetron is 143207-25-4.
What is the molecular formula of 7-Methoxy tropisetron?
The molecular formula of 7-Methoxy tropisetron is C18H22N2O3.
What is the molecular weight of 7-Methoxy tropisetron?
The molecular weight of 7-Methoxy tropisetron is 314.16 g/mol.
Where can I buy 7-Methoxy tropisetron?
You can request a quote for 7-Methoxy tropisetron directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Methoxy tropisetron?
Yes, KEHONG BIO provides custom synthesis services for 7-Methoxy tropisetron and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.