E 3753
TL;DR: E 3753 (CAS 14315-23-2) is a chemical compound with molecular formula C20H28F3N3O2 and molecular weight 399.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
E 3753
1-(tert-butylamino)-3-[1-(1-methylimidazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethoxy]propan-2-ol
Also Known As: E 3753, KST-1B0484, E-3753, 1-(tert-butylamino)-3-{1-(1-methyl-1h-imidazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethoxy}propan-2-ol, 2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[1-(1-methyl-1H-imidazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethoxy]-
| Molecular Formula | C20H28F3N3O2 |
|---|---|
| Molecular Weight | 399.21 g/mol |
| LogP | 2.4 |
| Topological Polar Surface Area | 59.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 399.21335 |
| Heavy Atoms | 28 |
| Complexity | 498.0 |
Chemical Identifiers
| CAS Number | 14315-23-2 |
|---|---|
| SMILES | CC(C)(C)NCC(COC(C)(C1=CC(=CC=C1)C(F)(F)F)C2=NC=CN2C)O |
| InChIKey | YBHBUAMCSUHDQV-UHFFFAOYSA-N |
Product Overview
E 3753 (CAS 14315-23-2), with molecular formula C20H28F3N3O2 and molecular weight 399.21 g/mol. IUPAC: 1-(tert-butylamino)-3-[1-(1-methylimidazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethoxy]propan-2-ol.
Chemical Property Profile of E 3753
Property Insights of E 3753
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for E 3753. With a topological polar surface area (TPSA) of 59.3 Ų, E 3753 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, E 3753 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of E 3753?
The CAS number of E 3753 is 14315-23-2.
What is the molecular formula of E 3753?
The molecular formula of E 3753 is C20H28F3N3O2.
What is the molecular weight of E 3753?
The molecular weight of E 3753 is 399.21 g/mol.
Where can I buy E 3753?
You can request a quote for E 3753 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for E 3753?
Yes, KEHONG BIO provides custom synthesis services for E 3753 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.