2'-hydroxy-3,4,5-trimethoxychalcone
TL;DR: 2'-hydroxy-3,4,5-trimethoxychalcone (CAS 142955-68-8) is a chemical compound with molecular formula C18H18O5 and molecular weight 314.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2-hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
Also Known As: 2'-hydroxy-3,4,5-trimethoxychalcone, 1-(2-hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one, 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-, (2E)-, N/A
| Molecular Formula | C18H18O5 |
|---|---|
| Molecular Weight | 314.12 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 65.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 314.11542 |
| Heavy Atoms | 23 |
| Complexity | 394.0 |
Chemical Identifiers
| CAS Number | 142955-68-8 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C=CC(=O)C2=CC=CC=C2O |
| InChIKey | SRSBUHVXNLHWHU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2'-hydroxy-3,4,5-trimethoxychalcone (CAS 142955-68-8), with molecular formula C18H18O5 and molecular weight 314.12 g/mol. IUPAC: 1-(2-hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one.
Chemical Property Profile of 2'-hydroxy-3,4,5-trimethoxychalcone
Property Insights of 2'-hydroxy-3,4,5-trimethoxychalcone
The XLogP value of 3.8 indicates that 2'-hydroxy-3,4,5-trimethoxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-hydroxy-3,4,5-trimethoxychalcone. Following Lipinski's Rule of Five, 2'-hydroxy-3,4,5-trimethoxychalcone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-hydroxy-3,4,5-trimethoxychalcone?
The CAS number of 2'-hydroxy-3,4,5-trimethoxychalcone is 142955-68-8.
What is the molecular formula of 2'-hydroxy-3,4,5-trimethoxychalcone?
The molecular formula of 2'-hydroxy-3,4,5-trimethoxychalcone is C18H18O5.
What is the molecular weight of 2'-hydroxy-3,4,5-trimethoxychalcone?
The molecular weight of 2'-hydroxy-3,4,5-trimethoxychalcone is 314.12 g/mol.
Where can I buy 2'-hydroxy-3,4,5-trimethoxychalcone?
You can request a quote for 2'-hydroxy-3,4,5-trimethoxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-hydroxy-3,4,5-trimethoxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 2'-hydroxy-3,4,5-trimethoxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.