10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one
TL;DR: 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one (CAS 1427-61-8) is a chemical compound with molecular formula C18H23FO2 and molecular weight 290.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-fluoro-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: 10-Fluoro-17beta-hydroxyestra-1,4-dien-3-one, 10-fluoro-17-hydroxyestra-1,4-dien-3-one, 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one, Estra-1,4-dien-3-one, 10-fluoro-17beta-hydroxy-, 10-fluoro-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydro-cyclopenta[a]phenanthren-3-one
| Molecular Formula | C18H23FO2 |
|---|---|
| Molecular Weight | 290.17 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 290.1682 |
| Heavy Atoms | 21 |
| Complexity | 551.0 |
Chemical Identifiers
| CAS Number | 1427-61-8 |
|---|---|
| SMILES | CC12CCC3C(C1CCC2O)CCC4=CC(=O)C=CC34F |
| InChIKey | KMESAHJOIFFQAU-UHFFFAOYSA-N |
Product Overview
10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one (CAS 1427-61-8), with molecular formula C18H23FO2 and molecular weight 290.17 g/mol. IUPAC: 10-fluoro-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one
Property Insights of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one. With a topological polar surface area (TPSA) of 37.3 Ų, 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one?
The CAS number of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one is 1427-61-8.
What is the molecular formula of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one?
The molecular formula of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one is C18H23FO2.
What is the molecular weight of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one?
The molecular weight of 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one is 290.17 g/mol.
Where can I buy 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one?
You can request a quote for 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one?
Yes, KEHONG BIO provides custom synthesis services for 10Beta-fluoro-17beta-hydroxy-estra-1,4-dien-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.