1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid
TL;DR: 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid (CAS 142253-55-2) is a chemical compound with molecular formula C15H10F2N2O2 and molecular weight 288.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3,4-difluorophenyl)-2-methylbenzimidazole-5-carboxylic acid
Also Known As: 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid, 1-(3,4-difluorophenyl)-2-methyl-1H-1,3-benzodiazole-5-carboxylic acid, 1-(3,4-difluorophenyl)-2-methylbenzimidazole-5-carboxylic acid, azetidine-1,3-dicarboxylic acidmono-tert-butyl ester, 1-(3,4-Difluorophenyl)-2-methyl-1H-benzo[d]imidazole-5-carboxylic acid
| Molecular Formula | C15H10F2N2O2 |
|---|---|
| Molecular Weight | 288.07 g/mol |
| LogP | 3.31032 |
| Topological Polar Surface Area | 55.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.07104 |
| Heavy Atoms | 21 |
| Complexity | 871.48126 |
Chemical Identifiers
| CAS Number | 142253-55-2 |
|---|---|
| SMILES | CC1=NC2=C(N1C3=CC(=C(C=C3)F)F)C=CC(=C2)C(=O)O |
Product Overview
1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid (CAS 142253-55-2), with molecular formula C15H10F2N2O2 and molecular weight 288.07 g/mol. IUPAC: 1-(3,4-difluorophenyl)-2-methylbenzimidazole-5-carboxylic acid.
Chemical Property Profile of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid
Property Insights of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid
The XLogP value of 3.31032 indicates that 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.12 Ų, 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid?
The CAS number of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid is 142253-55-2.
What is the molecular formula of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid?
The molecular formula of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid is C15H10F2N2O2.
What is the molecular weight of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid?
The molecular weight of 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid is 288.07 g/mol.
Where can I buy 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid?
You can request a quote for 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 1-(3,4-difluorophenyl)-2-methyl-1H-benzimidazole-5-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.