TSAO-a3T
TL;DR: TSAO-a3T (CAS 142102-81-6) is a chemical compound with molecular formula C27H47N3O8SSi2 and molecular weight 629.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methyl-3-prop-2-enylpyrimidine-2,4-dione
Also Known As: TSAO analog, TSAO-a3T, 3Allyl-2',5'diSilylSpiroT, (1-(2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl)-3-N-allylthymine)-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide), [1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-3-N-allylthymine]-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide)
| Molecular Formula | C27H47N3O8SSi2 |
|---|---|
| Molecular Weight | 629.26 g/mol |
| LogP | 3.71292 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 629.26227 |
| Heavy Atoms | 41 |
| Complexity | 1260.0 |
Chemical Identifiers
| CAS Number | 142102-81-6 |
|---|---|
| SMILES | CC1=CN(C(=O)N(C1=O)CC=C)[C@H]2[C@@H](C3([C@H](O2)CO[Si](C)(C)C(C)(C)C)C(=CS(=O)(=O)O3)N)O[Si](C)(C)C(C)(C)C |
| InChIKey | ZYAASSGDSGTPCS-HEXPWKSXSA-N |
Product Overview
TSAO-a3T (CAS 142102-81-6), with molecular formula C27H47N3O8SSi2 and molecular weight 629.26 g/mol. IUPAC: 1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methyl-3-prop-2-enylpyrimidine-2,4-dione.
Chemical Property Profile of TSAO-a3T
Property Insights of TSAO-a3T
The XLogP value of 3.71292 indicates that TSAO-a3T is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 146.0 Ų indicates high polarity, suggesting TSAO-a3T may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, TSAO-a3T has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TSAO-a3T?
The CAS number of TSAO-a3T is 142102-81-6.
What is the molecular formula of TSAO-a3T?
The molecular formula of TSAO-a3T is C27H47N3O8SSi2.
What is the molecular weight of TSAO-a3T?
The molecular weight of TSAO-a3T is 629.26 g/mol.
Where can I buy TSAO-a3T?
You can request a quote for TSAO-a3T directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TSAO-a3T?
Yes, KEHONG BIO provides custom synthesis services for TSAO-a3T and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.