TSAO-m5C
TL;DR: TSAO-m5C (CAS 142102-77-0) is a chemical compound with molecular formula C24H44N4O7SSi2 and molecular weight 588.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidin-2-one
Also Known As: TSAO analog, TSAO-m5C, 2',5'diSilyl-5MeSpiroC, (1-(2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl)-5-methylcytosine)-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide), (6R,8R,9R)-4-Amino-9-{[tert-butyldi(methyl)silyl]oxy}-6-({[tert-butyldi(methyl)silyl]oxy}methyl)-8-(2-hydroxy-4-imino-5-methylpyrimidin-1(4H)-yl)-1,7-dioxa-2lambda~6~-thiaspiro[4.4]non-3-ene-2,2-dione
| Molecular Formula | C24H44N4O7SSi2 |
|---|---|
| Molecular Weight | 588.25 g/mol |
| LogP | 3.34242 |
| Topological Polar Surface Area | 164.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 588.24695 |
| Heavy Atoms | 38 |
| Complexity | 1180.0 |
Chemical Identifiers
| CAS Number | 142102-77-0 |
|---|---|
| SMILES | CC1=CN(C(=O)N=C1N)[C@H]2[C@@H](C3([C@H](O2)CO[Si](C)(C)C(C)(C)C)C(=CS(=O)(=O)O3)N)O[Si](C)(C)C(C)(C)C |
| InChIKey | WXVQHOFJJQTAAY-CXFIUDIKSA-N |
Product Overview
TSAO-m5C (CAS 142102-77-0), with molecular formula C24H44N4O7SSi2 and molecular weight 588.25 g/mol. IUPAC: 4-amino-1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidin-2-one.
Chemical Property Profile of TSAO-m5C
Property Insights of TSAO-m5C
The XLogP value of 3.34242 indicates that TSAO-m5C is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 164.0 Ų indicates high polarity, suggesting TSAO-m5C may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, TSAO-m5C has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TSAO-m5C?
The CAS number of TSAO-m5C is 142102-77-0.
What is the molecular formula of TSAO-m5C?
The molecular formula of TSAO-m5C is C24H44N4O7SSi2.
What is the molecular weight of TSAO-m5C?
The molecular weight of TSAO-m5C is 588.25 g/mol.
Where can I buy TSAO-m5C?
You can request a quote for TSAO-m5C directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TSAO-m5C?
Yes, KEHONG BIO provides custom synthesis services for TSAO-m5C and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.