5Et-2',5'SilylSpiroU
TL;DR: 5Et-2',5'SilylSpiroU (CAS 142102-75-8) is a chemical compound with molecular formula C25H45N3O8SSi2 and molecular weight 603.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-ethylpyrimidine-2,4-dione
Also Known As: TSAO deriv., 5Et-2',5'SilylSpiroU, (1-(2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl)-5-ethyluracil)-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide), (6R,8R,9R)-4-Amino-9-{[tert-butyldi(methyl)silyl]oxy}-6-({[tert-butyldi(methyl)silyl]oxy}methyl)-8-(5-ethyl-4-hydroxy-2-oxopyrimidin-1(2H)-yl)-1,7-dioxa-2lambda~6~-thiaspiro[4.4]non-3-ene-2,2-dione, [1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-5-ethyluracil]-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide)
| Molecular Formula | C25H45N3O8SSi2 |
|---|---|
| Molecular Weight | 603.25 g/mol |
| LogP | 3.3075 |
| Topological Polar Surface Area | 155.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 9 |
| Exact Mass | 603.2466 |
| Heavy Atoms | 39 |
| Complexity | 1180.0 |
Chemical Identifiers
| CAS Number | 142102-75-8 |
|---|---|
| SMILES | CCC1=CN(C(=O)NC1=O)[C@H]2[C@@H](C3([C@H](O2)CO[Si](C)(C)C(C)(C)C)C(=CS(=O)(=O)O3)N)O[Si](C)(C)C(C)(C)C |
| InChIKey | DDDGNCKKEZVOKH-XNPIEGOSSA-N |
Product Overview
5Et-2',5'SilylSpiroU (CAS 142102-75-8), with molecular formula C25H45N3O8SSi2 and molecular weight 603.25 g/mol. IUPAC: 1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-ethylpyrimidine-2,4-dione.
Chemical Property Profile of 5Et-2',5'SilylSpiroU
Property Insights of 5Et-2',5'SilylSpiroU
The XLogP value of 3.3075 indicates that 5Et-2',5'SilylSpiroU is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 155.0 Ų indicates high polarity, suggesting 5Et-2',5'SilylSpiroU may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5Et-2',5'SilylSpiroU has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5Et-2',5'SilylSpiroU?
The CAS number of 5Et-2',5'SilylSpiroU is 142102-75-8.
What is the molecular formula of 5Et-2',5'SilylSpiroU?
The molecular formula of 5Et-2',5'SilylSpiroU is C25H45N3O8SSi2.
What is the molecular weight of 5Et-2',5'SilylSpiroU?
The molecular weight of 5Et-2',5'SilylSpiroU is 603.25 g/mol.
Where can I buy 5Et-2',5'SilylSpiroU?
You can request a quote for 5Et-2',5'SilylSpiroU directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5Et-2',5'SilylSpiroU?
Yes, KEHONG BIO provides custom synthesis services for 5Et-2',5'SilylSpiroU and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.