SilyriboT TSAO deriv.
TL;DR: SilyriboT TSAO deriv. (CAS 141684-48-2) is a chemical compound with molecular formula C18H29N3O8SSi and molecular weight 475.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(6R,8R,9R)-4-amino-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-9-hydroxy-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
Also Known As: SilyriboT TSAO deriv., (1-(5'-O-(tert-butyldimethylsilyl)-beta-D-xylofuranosyl)thymine)-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide), 4-Hydroxy-3-((2-t-butyl-5-methylpheny)thio)-6-(4-(2-methylthiazolemethoxy)phenyl)-2H-pyran-2-one, (6R,8R,9R)-4-Amino-6-({[tert-butyldi(methyl)silyl]oxy}methyl)-9-hydroxy-8-(4-hydroxy-5-methyl-2-oxopyrimidin-1(2H)-yl)-1,7-dioxa-2lambda~6~-thiaspiro[4.4]non-3-ene-2,2-dione, [1-[5'-O-(tert-butyldimethylsilyl)-.beta.-D-xylofuranosyl)thymine]-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide)
| Molecular Formula | C18H29N3O8SSi |
|---|---|
| Molecular Weight | 475.14 g/mol |
| LogP | 0.02402 |
| Topological Polar Surface Area | 166.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 475.14447 |
| Heavy Atoms | 31 |
| Complexity | 965.0 |
Chemical Identifiers
| CAS Number | 141684-48-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H](C3([C@H](O2)CO[Si](C)(C)C(C)(C)C)C(=CS(=O)(=O)O3)N)O |
| InChIKey | CDJVCWAMPWXXRB-JMCPPOTBSA-N |
Product Overview
SilyriboT TSAO deriv. (CAS 141684-48-2), with molecular formula C18H29N3O8SSi and molecular weight 475.14 g/mol. IUPAC: 1-[(6R,8R,9R)-4-amino-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-9-hydroxy-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of SilyriboT TSAO deriv.
Property Insights of SilyriboT TSAO deriv.
The XLogP value of 0.02402 suggests moderate lipophilicity, balancing water solubility and membrane permeability for SilyriboT TSAO deriv.. The TPSA of 166.0 Ų indicates high polarity, suggesting SilyriboT TSAO deriv. may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, SilyriboT TSAO deriv. has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SilyriboT TSAO deriv.?
The CAS number of SilyriboT TSAO deriv. is 141684-48-2.
What is the molecular formula of SilyriboT TSAO deriv.?
The molecular formula of SilyriboT TSAO deriv. is C18H29N3O8SSi.
What is the molecular weight of SilyriboT TSAO deriv.?
The molecular weight of SilyriboT TSAO deriv. is 475.14 g/mol.
Where can I buy SilyriboT TSAO deriv.?
You can request a quote for SilyriboT TSAO deriv. directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SilyriboT TSAO deriv.?
Yes, KEHONG BIO provides custom synthesis services for SilyriboT TSAO deriv. and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.