Losartan metabolite M5
TL;DR: Losartan metabolite M5 (CAS 141675-59-4) is a chemical compound with molecular formula C22H23ClN6O2 and molecular weight 438.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-chloro-5-(hydroxymethyl)-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-2-yl]butan-1-ol
Also Known As: Losartan metabolite M5, O-3-Hydroxy Losartan, ?-3-Hydroxy Losartan, OMEGA-3-HYDROXY LOSARTAN, 1-[4-chloro-5-(hydroxymethyl)-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-2-yl]butan-1-ol
| Molecular Formula | C22H23ClN6O2 |
|---|---|
| Molecular Weight | 438.16 g/mol |
| LogP | 3.7577 |
| Topological Polar Surface Area | 112.74 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 438.1571 |
| Heavy Atoms | 31 |
| Complexity | 1141.5349 |
Chemical Identifiers
| CAS Number | 141675-59-4 |
|---|---|
| SMILES | CCCC(C1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl)O |
Product Overview
Losartan metabolite M5 (CAS 141675-59-4), with molecular formula C22H23ClN6O2 and molecular weight 438.16 g/mol. IUPAC: 1-[4-chloro-5-(hydroxymethyl)-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-2-yl]butan-1-ol.
Chemical Property Profile of Losartan metabolite M5
Property Insights of Losartan metabolite M5
The XLogP value of 3.7577 indicates that Losartan metabolite M5 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 112.74 Ų falls within the moderate polarity range, balancing permeability and solubility for Losartan metabolite M5. Following Lipinski's Rule of Five, Losartan metabolite M5 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losartan metabolite M5?
The CAS number of Losartan metabolite M5 is 141675-59-4.
What is the molecular formula of Losartan metabolite M5?
The molecular formula of Losartan metabolite M5 is C22H23ClN6O2.
What is the molecular weight of Losartan metabolite M5?
The molecular weight of Losartan metabolite M5 is 438.16 g/mol.
Where can I buy Losartan metabolite M5?
You can request a quote for Losartan metabolite M5 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losartan metabolite M5?
Yes, KEHONG BIO provides custom synthesis services for Losartan metabolite M5 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.