Silperisone structure

Silperisone

TL;DR: Silperisone (CAS 140944-31-6) is a chemical compound with molecular formula C15H24FNSi and molecular weight 265.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(4-fluorophenyl)methyl-dimethyl-(piperidin-1-ylmethyl)silane

Also Known As: Silperisone, Silperisone [INN], silperisona, silperisonum, 1-(((p-Fluorobenzyl)dimethylsilyl)methyl)piperidine

CAS: 140944-31-6
Molecular Formula C15H24FNSi
Molecular Weight 265.17 g/mol
LogP 3.6409
Topological Polar Surface Area 3.2 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 4
Exact Mass 265.1662
Heavy Atoms 18
Complexity 243.0

Chemical Identifiers

CAS Number 140944-31-6
SMILES C[Si](C)(CC1=CC=C(C=C1)F)CN2CCCCC2
InChIKey LOCRKLISCBHQPO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Organometallic Reagents (4 patents) Pharmaceutical Intermediates (16 patents)

Product Overview

Silperisone (CAS 140944-31-6), with molecular formula C15H24FNSi and molecular weight 265.17 g/mol. IUPAC: (4-fluorophenyl)methyl-dimethyl-(piperidin-1-ylmethyl)silane.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Silperisone

XLogP
3.6409
TPSA (Topological Polar Surface Area)
3.2
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
4
Heavy Atoms
18
Complexity
243.0
Exact Mass
265.1662
Monoisotopic Mass
265.1662
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Silperisone

The XLogP value of 3.6409 indicates that Silperisone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Silperisone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Silperisone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Silperisone?

The CAS number of Silperisone is 140944-31-6.

What is the molecular formula of Silperisone?

The molecular formula of Silperisone is C15H24FNSi.

What is the molecular weight of Silperisone?

The molecular weight of Silperisone is 265.17 g/mol.

Where can I buy Silperisone?

You can request a quote for Silperisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Silperisone?

Yes, KEHONG BIO provides custom synthesis services for Silperisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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