D 381a
TL;DR: D 381a (CAS 14089-49-7) is a chemical compound with molecular formula C11H15ClF3NO and molecular weight 269.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-2-methyl-1-[4-(trifluoromethyl)phenyl]propan-1-ol;hydrochloride
Also Known As: D 381a, alpha-(1-Amino-1-methylethyl)-4-(trifluoromethyl)benzenemethanol hydrochloride, Benzenemethanol, alpha-(1-amino-1-methylethyl)-4-(trifluoromethyl)-, hydrochloride, Benzyl alcohol, alpha-(1-amino-1-methylethyl)-p-(trifluoromethyl)-, hydrochloride, 2-amino-2-methyl-1-[4-(trifluoromethyl)phenyl]propan-1-ol hydrochloride
| Molecular Formula | C11H15ClF3NO |
|---|---|
| Molecular Weight | 269.08 g/mol |
| LogP | 2.8979 |
| Topological Polar Surface Area | 46.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 269.07944 |
| Heavy Atoms | 17 |
| Complexity | 232.0 |
Chemical Identifiers
| CAS Number | 14089-49-7 |
|---|---|
| SMILES | CC(C)(C(C1=CC=C(C=C1)C(F)(F)F)O)N.Cl |
| InChIKey | CCOIXAOAVLUWFI-UHFFFAOYSA-N |
Product Overview
D 381a (CAS 14089-49-7), with molecular formula C11H15ClF3NO and molecular weight 269.08 g/mol. IUPAC: 2-amino-2-methyl-1-[4-(trifluoromethyl)phenyl]propan-1-ol;hydrochloride.
Chemical Property Profile of D 381a
Property Insights of D 381a
The XLogP value of 2.8979 suggests moderate lipophilicity, balancing water solubility and membrane permeability for D 381a. With a topological polar surface area (TPSA) of 46.3 Ų, D 381a exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, D 381a has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of D 381a?
The CAS number of D 381a is 14089-49-7.
What is the molecular formula of D 381a?
The molecular formula of D 381a is C11H15ClF3NO.
What is the molecular weight of D 381a?
The molecular weight of D 381a is 269.08 g/mol.
Where can I buy D 381a?
You can request a quote for D 381a directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for D 381a?
Yes, KEHONG BIO provides custom synthesis services for D 381a and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.