Amphotericin A
TL;DR: Amphotericin A (CAS 1405-32-9) is a chemical compound with molecular formula C47H75NO17 and molecular weight 925.50 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
Also Known As: Amphotericin A, 3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
| Molecular Formula | C47H75NO17 |
|---|---|
| Molecular Weight | 925.50 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 320.0 Ų |
| Hydrogen Bond Donors | 12 |
| Hydrogen Bond Acceptors | 18 |
| Rotatable Bonds | 3 |
| Exact Mass | 925.5035 |
| Heavy Atoms | 65 |
| Complexity | 1620.0 |
Chemical Identifiers
| CAS Number | 1405-32-9 |
|---|---|
| SMILES | CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O |
| InChIKey | QGGFZZLFKABGNL-UHFFFAOYSA-N |
Product Overview
Amphotericin A (CAS 1405-32-9), with molecular formula C47H75NO17 and molecular weight 925.50 g/mol. IUPAC: 33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid.
Chemical Property Profile of Amphotericin A
Property Insights of Amphotericin A
The XLogP value of -0.2 indicates that Amphotericin A is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 320.0 Ų indicates high polarity, suggesting Amphotericin A may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amphotericin A has 12 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amphotericin A?
The CAS number of Amphotericin A is 1405-32-9.
What is the molecular formula of Amphotericin A?
The molecular formula of Amphotericin A is C47H75NO17.
What is the molecular weight of Amphotericin A?
The molecular weight of Amphotericin A is 925.50 g/mol.
Where can I buy Amphotericin A?
You can request a quote for Amphotericin A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amphotericin A?
Yes, KEHONG BIO provides custom synthesis services for Amphotericin A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.