4-Cyano-4'-(Trifluoromethyl)biphenyl structure

4-Cyano-4'-(Trifluoromethyl)biphenyl

TL;DR: 4-Cyano-4'-(Trifluoromethyl)biphenyl (CAS 140483-60-9) is a chemical compound with molecular formula C14H8F3N and molecular weight 247.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[4-(trifluoromethyl)phenyl]benzonitrile

Also Known As: 4-Cyano-4'-(Trifluoromethyl)biphenyl, 4-[4-(trifluoromethyl)phenyl]benzonitrile, 4'-(Trifluoromethyl)[1,1'-biphenyl]-4-carbonitrile, 4-(4-trifluoromethylphenyl)benzonitrile, 4-Cyano-4''-(Trifluoromethyl)biphenyl

CAS: 140483-60-9
Molecular Formula C14H8F3N
Molecular Weight 247.06 g/mol
LogP 4.24408
Topological Polar Surface Area 23.79 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 247.06088
Heavy Atoms 18
Complexity 574.4216

Chemical Identifiers

CAS Number 140483-60-9
SMILES C1=CC(=CC=C1C#N)C2=CC=C(C=C2)C(F)(F)F

Product Overview

4-Cyano-4'-(Trifluoromethyl)biphenyl (CAS 140483-60-9), with molecular formula C14H8F3N and molecular weight 247.06 g/mol. IUPAC: 4-[4-(trifluoromethyl)phenyl]benzonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Cyano-4'-(Trifluoromethyl)biphenyl

XLogP
4.24408
TPSA (Topological Polar Surface Area)
23.79
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
18
Complexity
574.4216
Exact Mass
247.06088
Monoisotopic Mass
247.06088
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Cyano-4'-(Trifluoromethyl)biphenyl

The XLogP value of 4.24408 indicates that 4-Cyano-4'-(Trifluoromethyl)biphenyl is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.79 Ų, 4-Cyano-4'-(Trifluoromethyl)biphenyl exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Cyano-4'-(Trifluoromethyl)biphenyl has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Cyano-4'-(Trifluoromethyl)biphenyl?

The CAS number of 4-Cyano-4'-(Trifluoromethyl)biphenyl is 140483-60-9.

What is the molecular formula of 4-Cyano-4'-(Trifluoromethyl)biphenyl?

The molecular formula of 4-Cyano-4'-(Trifluoromethyl)biphenyl is C14H8F3N.

What is the molecular weight of 4-Cyano-4'-(Trifluoromethyl)biphenyl?

The molecular weight of 4-Cyano-4'-(Trifluoromethyl)biphenyl is 247.06 g/mol.

Where can I buy 4-Cyano-4'-(Trifluoromethyl)biphenyl?

You can request a quote for 4-Cyano-4'-(Trifluoromethyl)biphenyl directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Cyano-4'-(Trifluoromethyl)biphenyl?

Yes, KEHONG BIO provides custom synthesis services for 4-Cyano-4'-(Trifluoromethyl)biphenyl and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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